A BACTERIAL BINARY TOXIN SYSTEM THAT KILLS BOTH INSECTS AND AQUATIC CRUSTACEANS: PHOTORHABDUS INSECT-RELATED TOXINS A AND B.

A bacterial binary toxin system that kills both insects and aquatic crustaceans: Photorhabdus insect-related toxins A and B.

Photorhabdus insect-related toxins A and B (PirA and PirB) were first recognized as insecticidal toxins from Photorhabdus luminescens.However, subsequent studies showed that their homologs from Vibrio parahaemolyticus also play critical roles in the pathogenesis of acute hepatopancreatic necrosis disease (AHPND) in shrimps.Based on the structural f

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Developing a complex intervention to support pregnant women with mild to moderate anxiety: application of the Medical Research Council framework

Abstract Background To design and develop an intervention to support women with symptoms of mild to moderate anxiety in pregnancy.Methods The development followed the MRC framework for complex interventions, utilising psychological theory, review level evidence and professional and public involvement.Two systematic reviews were completed which help

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Plant-specific tail-anchored coiled-coil protein MAG3 stabilizes Golgi-associated ERESs to facilitate protein exit from the ER

Abstract Endoplasmic reticulum Salmon exit sites (ERESs) are ER subdomains where coat protein complex II carriers are assembled for ER-to-Golgi transport.We previously proposed a dynamic capture-and-release model of ERESs by Golgi stacks in plants.However, how ERESs and Golgi stacks maintain a stable interaction in plant cells with vigorous cytopla

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